Epidemiology of Dry Eye in Germany II (Dry-Eye II): Keratography-Based Examinations of the Ocular Surface

Project goals

In the 5,000 participants of the Düsseldorf subcohort of NAKO, ocular surface examinations are conducted using the Placido disc principle. This Level-3 project allows, for the first time within this study, an objective determination of dry eye parameters and will contribute to a better understanding of the risk factors and prevalence of the disease in Germany.

Dry eye is a multifactorial disease of the tear film and ocular surface that leads to a significant loss of quality of life for individuals and incurs costs for society. It is considered one of the four most common eye disorders. International epidemiological studies report prevalence rates ranging from 11 to 36 percent, depending on the population studied.

In the Level-3 project Epidemiology of Dry Eye in Germany II (Dry-Eye II), 5,000 participants from the Düsseldorf subcohort of the German National Cohort (NAKO) undergo an examination of the tear film and ocular surface using the Oculus Keratograph 5. This project allows, for the first time, an objective determination of dry eye parameters and will help to better understand the risk factors and prevalence of the disease. Additionally, it will enable a reassessment of the validity of the Dry-Eye I questionnaire, as well as the relationships with quality of life, other diseases, and treatment costs.